报告人：Philip Maini, Oxford University
报告人简介:Philip K. Maini, 牛津大学教授，并于2015年聘为数学生物学科Inaugural Statutory教授，英国皇家学院院士, 曾担任Bulletin of Mathematical Biology主编及多个国际期刊的编委会成员，是IMA (FIMA) Fellow， SIAM Fellow. 发表论文350余篇，荣获2009年LMS Naylor 奖和2017年数学生物学协会Arthur T. Winfree Prize.
报告题目：Elucidating the Hallmarks of Collective Cell Migration
摘要： Collective cell migration is a very common feature of many processes in early development, wound healing, and aspects of cancerous tumour dynamics. I will review two areas of application in which we have been working for several years: (a) cranial neural crest cell migration - here, we have used a hybrid cell-based mathematical model that, in collaboration with our experimental colleagues, has helped us reveal new insights into how these cells signal to each other as they move and, as a by-product, suggested a possible cancer treatment; (b) angiogenesis - this is the process by which new blood vessels are created - we use a systematic coarse-grain analysis to derive a partial differential equation model for this phenomenon and find, to our surprise, that it differs from the classical, phenomenologically derived, "snail-trail" model. We investigate the similarities and differences between the two models. In addressing these two problems, we are beginning to determine the common features of collective cell migration and define the "hallmarks of collective cell migration.
报告时间：7月7日, 20:30-22:00(Harbin), 13:30-15:00(London), 14:30-16:00(Paris)
Zoom webinar ID: 976 5297 1842